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John C. Wood, MD, PhD

Professor
University of Southern California

Dr. John Wood is Professor of Pediatrics, Radiology, and Bioengineering at the University of Southern California. He also serves as the Director of Cardiovascular MRI Medical Director of the Clinical Trials Unit at Children’s Hospital Los Angeles. Dr. Wood graduated in from UC. Davis (Electrical Engineering) in 1984 and received his MD/PhD (Bioengineering) from the University of Michigan in 1994. He performed his residency and fellowship in Pediatric Cardiology at Yale and joined Children’s Hospital Los Angeles/USC Keck School of Medicine in 1999. Clinically, specializes in the MRI assessment of congenital heart disease and iron overload syndromes.
Dr. Wood has been studying the cardiovascular consequences of hemoglobinopathies for almost a decade. He is one of the pioneer’s of MRI-based cardiac and liver iron measurements but also studies oral chelation strategies in animals and humans. He was the principle investigator for the Early Detection of Iron Cardiomyopathy Trial whose goal was to identify earlier markers of cardiac dysfunction in thalassemia syndromes. Dr. Wood also has studied pancreatic and pituitary iron burden by MRI and their functional correlates.
In the past nine years, he has been studying the mechanisms and treatment of peripheral and cerebral vasculopathy in chronic anemia syndromes, exploring the links between abnormal red cell mechanics and vascular dynamics in hemoglobinopathy patients. His research focuses on mechanisms and predictors of progressive white matter damage in patients with anemia.

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