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Oral Abstract

Oral Abstract Science #1- Advances in Cardiac MRI Techniques

Comparative Evaluation of Third-Order Motion-Compensated in Vivo Diffusion Tensor CMR Across Cardiac Phases Using an Ultra-High-Gradient Strength Clinical Scanner

Thursday, January 30, 2025
6:00 PM – 6:10 PM East Coast USA Time
Location: Blue Room
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Figure 2&3 show DT-CMR maps (FA, MD, HA, E2A) generated from in-vivo SMS STEAM data reconstructed with both a conventional and the proposed SMS (10 averages) technique, SB data (5 averages to match acquisition duration for 2 slices). All data were acquired with a 2x PI acceleration. The proposed method produces good quality DT-CMR parameter maps without significant artifacts, comparable to the results obtained with time-matched SB data, while the conventional SMS reconstruction method exhibits lower MD values and residual aliasing in the HA map. 




Conclusion:

We successfully demonstrated the feasibility of the extended SENSE reconstruction for in-vivo and ex-vivo DT-CMR with both SMS and in-plane parallel imaging acceleration, showing superior leakage artifact suppression compared to a conventional two-step GRAPPA approach. This reconstruction method could enable more widespread use of SMS acceleration for in-vivo and ex-vivo DT-CMR without the typical artifacts associated with slice leakage. 

Figure 1. Retrospective SMS simulation results (SMS=2, PI=2) with diffusion-weighted images reconstructed using the conventional (two-step) and the proposed (one-step extended SENSE) methods at b=0, 500, and 1000 s/mm2, along with corresponding error and SSIM maps. Notably, the proposed method significantly suppresses residual leakage artifacts.

Figure 2. Prospective FA, MD, HA, and E2A maps for SMS reconstructed images using the conventional two-step reconstruction and the proposed extended SENSE reconstruction (SMS=2, PI=2), compared to single-band data (PI=2) obtained in the same position. The three sets share the same acquisition time.

Figure 3. Prospective results equivalent to those in Figure 2, but for the basal slice.